Research Article
Antibacterial Derivatives of Ciprofloxacin to Inhibit Growth of Necrotizing Fasciitis Associated Penicillin Resistant Escherichia coli
Table 1
Molecular properties of drugs.
| Drug | Log | Polar surface area () | Number of atoms | Molecular weight | Number of oxygen and nitrogen | Number of –OH and | Violations of rule of 5 | Number of rotatable bonds | Molecular volume () |
| Drug 1 | | 74.6 | 24 | 331.3 | 6 | 2 | 0 | 3 | 285.5 | Drug 2 | 0.437 | 63.6 | 27 | 373.4 | 6 | 1 | 0 | 6 | 336.6 | Drug 3 | 1.50 | 63.6 | 29 | 401.5 | 6 | 1 | 0 | 8 | 370.2 | Drugs 4 | 3.02 | 63.6 | 32 | 443.6 | 6 | 1 | 0 | 11 | 420.6 |
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