Antibacterial Derivatives of Ciprofloxacin to Inhibit Growth of Necrotizing Fasciitis Associated Penicillin Resistant <i>Escherichia coli</i>

<table class="table-group" id="tab4"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td align="left">pH</td><td align="center">Ciprofloxacin</td><td align="center">Ciprofloxacin propyl ester</td><td align="center">Ciprofloxacin pentyl ester</td><td align="center">Ciprofloxacin octyl ester</td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td align="left">3.0</td><td align="center">0.09</td><td align="center">0.37</td><td align="center">1.32</td><td align="center">2.69</td></tr><tr><td align="left">5.5</td><td align="center"><span style="width: 38.462502px;"><svg height="11.125" id="M43" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 38.462502 11.125" width="38.462502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg></span></td><td align="center">0.42</td><td align="center">1.37</td><td align="center">2.73</td></tr><tr><td align="left">7.4</td><td align="center"><span style="width: 38.462502px;"><svg height="11.225" id="M44" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 38.462502 11.225" width="38.462502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg></span></td><td align="center">1.40</td><td align="center">2.35</td><td align="center">3.70</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Log <svg height="11.175" id="M42" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 13.775 11.175" width="13.775" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,11.113)"><path d="M780 372q0 -191 -178 -297q-128 -75 -335 -75h-250l7 27q61 7 77 22t28 76l77 398q11 62 0 76.5t-77 22.5l6 28h292q164 0 258.5 -67.5t94.5 -210.5zM678 375q0 119 -73 180.5t-201 61.5q-62 0 -82 -13q-17 -7 -25 -53l-80 -427q-8 -47 -4 -62t26 -20q24 -6 80 -6
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</svg> values of ciprofloxacin derivatives by pH.

Journal of Pharmaceutics

tab4

Table 4

Table 4: Antibacterial Derivatives of Ciprofloxacin to Inhibit Growth of Necrotizing Fasciitis Associated Penicillin Resistant <i>Escherichia coli</i> 

Journal of Pharmaceutics

Antibacterial Derivatives of Ciprofloxacin to Inhibit Growth of Necrotizing Fasciitis Associated Penicillin Resistant Escherichia coli

Table 4