Biological Atomic Force Microscopy for Imaging Gold-Labeled Liposomes on Human Coronary Artery Endothelial Cells
Figure 3
AFM images of FITC-labeled liposomes coupled to 90 nm gold particles and scanned on fresh cleaved mica. (a) Height image with section analysis measuring the diameter of three particles (95, 86, and 80 nm, resp.) that made up a typical gold-liposome cluster. (b) Additional digital zoom to 1 taken from the original scan at 2.5 μm (x-y). The DLS analysis showed that the gold-liposome complexes had a diameter of nm. Tapping mode in air using RTESP cantilevers ( = 262–325 kHz, = 20–80 N/m).
