Dissolution Rate Enhancement, Design and Development of Buccal Drug Delivery of Darifenacin Hydroxypropyl <i>β</i>-Cyclodextrin Inclusion Complexes

<table class="table-group" id="tab7"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td align="left">Formulation code</td><td align="center">Bioadhesive strength (g)</td><td align="center">Force of adhesion (N)</td><td align="center">Bond strength (N m<sup>−2</sup>)</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td align="left">Hb1</td><td align="center">10.15 ± 0.67</td><td align="center">0.099</td><td align="center">994.7</td></tr><tr><td align="left">Hb2</td><td align="center">12.02 ± 1.38</td><td align="center">0.117</td><td align="center">1177.96</td></tr><tr><td align="left">Hb3</td><td align="center">12.62 ± 1.22</td><td align="center">0.123</td><td align="center">1236.76</td></tr><tr><td align="left">Hb4</td><td align="center">13.87 ± 1.42</td><td align="center">0.135</td><td align="center">1359.26</td></tr><tr><td align="left">Hb5</td><td align="center">14.98 ± 1.54</td><td align="center">0.146</td><td align="center">1468.804</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Bioadhesive parameters of HPMC K100M CR patches.

Journal of Pharmaceutics

tab7

Table 7

Table 7: Dissolution Rate Enhancement, Design and Development of Buccal Drug Delivery of Darifenacin Hydroxypropyl <i>β</i>-Cyclodextrin Inclusion Complexes 

Table 7 | Dissolution Rate Enhancement, Design and Development of Buccal Drug Delivery of Darifenacin Hydroxypropyl β-Cyclodextrin Inclusion Complexes 