Formulation Development and Evaluation of Fast Disintegrating Tablet of Cetirizine Hydrochloride: A Novel Drug Delivery for Pediatrics and Geriatrics

Table 2

Formula for 1 tablet (200 mg) for the optimization of Polyvinylpyrrolidone K-30 or Microcrystalline Cellulose with optimized concentration of Sodium Starch Glycolate.

Formula number	Contents
	Cetirizine Hydrochloride (mg)	SSG (mg)	PVP K-30 (mg)	MCC (mg)	Sodium Stearyl Fumarate (mg)	Talc (mg)	Sodium Saccharin (mg)	Mannitol (mg)
F1	5	8	2	—	2	2	5	176
F2	5	8	4	—	2	2	5	174
F3	5	8	6	—	2	2	5	172
F4	5	8	8	—	2	2	5	170
F5	5	8	10	—	2	2	5	168
F6	5	8	12	—	2	2	5	166
F7	5	8	14		2	2	5	164
F8	5	8	—	2	2	2	5	176
F9	5	8	—	4	2	2	5	174
F10	5	8	—	6	2	2	5	172
F11	5	8	—	8	2	2	5	170
F12	5	8	—	10	2	2	5	168
F13	5	8	—	12	2	2	5	166
F14	5	8	—	14	2	2	5	164