Research Article
In Vitro and In Vivo Correlation of Colon-Targeted Compression-Coated Tablets
Table 6
In vivo absorption parameters of PDL from various dosage form.
| Parameters | Intravenous (IV) | Core tablet | Compression-coated tablet
|
| (ng/mL) | 1624.29 ± 15.22 | 1172.28 ± 22.98 | 245.40 ± 10.42 | (min) | 5 | 60 | 600 | (min·ng/mL) | 104537 ± 1292.80 | 146075 ± 4133.50 | 83926.37 ± 1469.03 | MRT (min) | 130.05 ± 2.25 | 138.33 ± 5.74 | 572.33 ± 7.90 |
|
|