In Vitro and In Vivo Correlation of Colon-Targeted Compression-Coated Tablets

Table 6

In vivo absorption parameters of PDL from various dosage form.

Parameters	Intravenous (IV)	Core tablet	Compression-coated tablet
(ng/mL)	1624.29 ± 15.22	1172.28 ± 22.98	245.40 ± 10.42
(min)	5	60	600
(min·ng/mL)	104537 ± 1292.80	146075 ± 4133.50	83926.37 ± 1469.03
MRT (min)	130.05 ± 2.25	138.33 ± 5.74	572.33 ± 7.90