The Role of Vitamin D and Vitamin D Receptor in Immunity to Leishmania major Infection
Figure 7
NO and IL-12p40 production by host cells. C57BL/6 WT (closed bars) and VDRKO (open bars) mice. DC were treated with IFNγ and/or 1,25D3 for 24 hr prior to being infected at a ratio of 5 : 1 with L. major. The cells were infected for 4 hr and washed to remove extracellular parasites. Supernatants were harvested 48 hr after infection and analyzed for production of NO (a) and IL-12p40 (b). Mean ± standard error is presented; (). .
