Helminths: Immunoregulation and Inflammatory Diseases—Which Side Are Trichinella spp. and Toxocara spp. on?

Table 2

Suppression of experimental inflammatory diseases by parasite-derived antigens.

Helminth	Antigen	Model	Reference
Trichinella spiralis	Soluble antigens of muscle larvae	EAE; DNBS-induced colitis	[77]; [78]
Trichuris suis	Soluble antigens of adult worm	EAE	[77]
Ancylostoma ceylanicum	Soluble and excretory-secretory antigens of adult worm	DSS-induced colitis	[79]
Hymenolepis diminuta	Soluble antigens of adult worm	DNBS-induced colitis	[80]
Heligmosomoides polygyrus	Excretory-secretory antigens (HES) of adult worm	EAAI	[73]
Ancylostoma caninum	Excretory-secretory antigens of adult worm	TNBS-induced colitis	[81]
Acanthocheilonema vitae	ES-62	Collagen-induced arthritis	[82]
Schistosoma mansoni	Soluble antigens of adult worm	TNBS-induced colitis	[81]
	SEA and soluble adult worm antigen	T1D	[83]
	Recombinant proteins (Sm22·6, Sm29) and soluble adult worm fraction (PIII)	EAAI	[84]
Schistosoma japonicum	SEA	EAAI	[85]
Nippostrongylus brasiliensis	Excretory-secretory antigens (NES) of adult worm	EAAI	[86]
Ascaris suum	Soluble antigens of adult worm	EAAI	[87]

EAE: experimental autoimmune encephalomyelitis; DNBS: dinitrobenzene sulfonic acid; TNBS: trinitrobenzene sulfonic acid; DSS: dextran sodium sulfate; T1D: type 1 diabetes; EAAI: experimental allergic airway inflammation.