Cajachalcone: An Antimalarial Compound from Cajanus cajan Leaf Extract

Table 1

Yield and in vitro antiplasmodial activity of Cajanus cajan leaf fractions and compounds.

Fractions/compounds/drug	Yield (%)	IC50 values with P. falciparum, K1 in µg/mL (µM)
Hexane	17.5	62.5
Dichloromethane	23.0	31.3
Ethyl acetate	20.5	15.6
Aq. methanol	36.5	31.3
Compound 1 (chalcone)	3.8	2.0 (7.40)
Compound 2	5.3	5.4 (18.37)
Compound 3	8.7	5.6
Chloroquine phosphate		0.2 (0.66)