MHC-DRB1/DQB1 Gene Polymorphism and Its Association with Resistance/Susceptibility to Cystic Echinococcosis in Chinese Merino Sheep

Table 1

Genotypic frequencies of DRB1 in Chinese Merino sheep with and without Cystic Echinococcosis.

Cystic Echinococcosis negative			Cystic Echinococcosis positive
Genotype	Number	Frequency	Genotype	Number	Frequency
SacI aa	42	0.3853	SacI aa	47	0.4700
SacI ab	58	0.5321*	SacI ab	38	0.3800
SacI bb	9	0.0826	SacI bb	15	0.1500
Hin1I aa	15	0.1376	Hin1I aa	14	0.1414
Hin1I ab	55	0.5046	Hin1I ab	43	0.4343
Hin1I bb	39	0.3578	Hin1I bb	42	0.4243
SacII aa	65	0.7471	SacII aa	50	0.6250
SacII ab	13	0.1494	SacII ab	22	0.2750*
SacII bb	9	0.1035	SacII bb	8	0.1000
MvaI aa	1	0.0115	MvaI aa	0	0
MvaI bb	68	0.7816**	MvaI bb	45	0.5556
MvaI cc	1	0.0115	MvaI cc	4	0.0494
MvaI dd	0	0	MvaI dd	0	0
MvaI ab	0	0	MvaI ab	0	0
MvaI ac	0	0	MvaI ac	1	0.0124
MvaI bc	17	0.1954	MvaI bc	31	0.3827**
HaeIII aa	17	0.1651	HaeIII aa	11	0.1100
HaeIII bb	9	0.0874	HaeIII bb	4	0.0400
HaeIII cc	5	0.0485	HaeIII cc	7	0.0700
HaeIII dd	0	0	HaeIII dd	1	0.0100
HaeIII ee	11	0.1068*	HaeIII ee	2	0.0200
HaeIII ff	11	0.1068	HaeIII ff	8	0.0800
HaeIII ab	1	0.0097	HaeIII ab	4	0.0400
HaeIII ac	12	0.1165	HaeIII ac	13	0.1300
HaeIII ae	1	0.0097	HaeIII ae	4	0.0400
HaeIII bd	1	0.0097	HaeIII bd	9	0.0900**
HaeIII be	2	0.0194	HaeIII be	5	0.0500
HaeIII cd	6	0.0583	HaeIII cd	0	0
HaeIII ce	16	0.1554	HaeIII ce	7	0.0700
HaeIII df	5	0.0485	HaeIII df	13	0.1300*
HaeIII ef	6	0.0583	HaeIII ef	12	0.1200

Note: the same genotypes of DRB1 in Chinese Merino sheep with and without Cystic Echinococcosis, ^∗𝑃<0.05, ^∗∗𝑃<0.01.