Antiplasmodial Effect of Anthocleista vogelii on Albino Mice Experimentally Infected with Plasmodium berghei berghei (NK 65)

Table 2

Acute toxicity (LD₅₀) of A. vogelii after 72 hours.

Group	Number of mice	Dosage (mg/kg/bw)	% mortality
1	4	1000	0
2	4	2000	0
3	4	3000	75
4	4	5000	100
5	4	6000	100
6	4	—	0

LD₅₀ of A. vogelii (𝑥) = √𝑎𝑏,
where 𝑎 = maximum dose with 0% mortality = 2000;
   𝑏 = minimum dose with 100% mortality = 5000;
   𝑥 = √2000×5000   = √10000000   = 3162 mg/kg body weight.