Increased severity of arthritis in coinfected BALB/c mice 30 days after infection versus single infection; no change in C3H/HeJ mice
Equal severity of carditis in BALB/c and C3H/HeJ coinfected and singly infected mice
Significant decrease in IL-10 and IL-13 in coinfected BALB/c mice 30 days after infection; no change in C3H/HeJ mice
Significant decrease in IgG in coinfected BALB/c mice 15 days after infection which returned to baseline 30 days after infection; no change in C3H/HeJ mice
Equal severity of arthritis in coinfected versus singly infected C3H/HeN mice or BALB/c mice
Equal spleen weights in C3H/HeN or BALB/c coinfected versus singly infected mice
N/A
Equal parasitemia in C3H/HeN or BALB/c coinfected versus singly infected mice; elevated LDH
Symptom severity assessed by patient self-report. Symptom severity assessed by clinical exam using criteria set forth by the American College of Rheumatology Glossary Joint Exam.