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Journal of Probability and Statistics
Volume 2012 (2012), Article ID 375935, 19 pages
http://dx.doi.org/10.1155/2012/375935
Research Article

Predicting Disease Onset from Mutation Status Using Proband and Relative Data with Applications to Huntington's Disease

1Department of Biostatistics, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY 10032, USA
2Department of Statistics, Texas A&M University, College Station, TX 77843, USA
3Departments of Neurology and Psychiatry and Sergievsky Center and the Taub Institute, Columbia University Medical Center, New York, NY 10032, USA
4Department of Psychiatry and Biostatistics (Secondary), University of Iowa, Iowa City, IA 52242, USA

Received 15 December 2011; Accepted 22 February 2012

Academic Editor: Yongzhao Shao

Copyright © 2012 Tianle Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Tianle Chen, Yuanjia Wang, Yanyuan Ma, Karen Marder, and Douglas R. Langbehn, “Predicting Disease Onset from Mutation Status Using Proband and Relative Data with Applications to Huntington's Disease,” Journal of Probability and Statistics, vol. 2012, Article ID 375935, 19 pages, 2012. doi:10.1155/2012/375935