Predicting Disease Onset from Mutation Status Using Proband and Relative Data with Applications to Huntington's Disease

Table 3

Descriptive statistics of the COHORT proband data.

		Numbers and ages for a CAG repeat length
		36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57+	Total
At risk	Number	2	5	15	21	43	55	68	57	31	28	18	9	5	2	1	0	2	0	0	0	0	0	362
	Ave age	61	64	48	55	50	45	42	39	37	31	34	34	27	23	30		35						42
	Min age	60	61	26	37	25	21	21	18	19	19	20	21	20	21	30		23						18
	Max age	62	69	66	70	88	67	71	62	51	44	51	53	40	25	30		47						88
	sd	1	3	11	9	14	11	11	10	9	7	9	9	9	3	.		17						13
	%	0.6	1.4	4.1	5.8	11.9	15.2	18.8	15.7	8.6	7.7	5.0	2.5	1.4	0.6	0.3	0.0	0.6	0.0	0.0	0.0	0.0	0.0
Affected	Number	2	1	6	7	67	128	148	144	143	93	83	47	34	21	18	9	7	10	6	3	3	15	995
	Ave age	54	68	55	53	60	55	51	48	44	41	38	36	33	31	31	30	28	23	26	26	23	20	45
	Min age	49	68	46	25	37	28	17	19	21	16	25	21	20	19	22	23	22	11	18	25	17	12	11
	Max age	59	68	67	77	82	76	76	67	67	58	53	48	46	44	39	35	35	29	31	29	28	27	82
	sd	7	.	7	19	10	9	9	8	8	8	6	6	6	6	5	4	5	6	5	2	6	4	12
	%	0.2	0.1	0.6	0.7	6.7	12.9	14.9	14.5	14.4	9.3	8.3	4.7	3.4	2.1	1.8	0.9	0.7	1.0	0.6	0.3	0.3	1.5
Total	Number	4	6	21	28	110	183	216	201	174	121	101	56	39	23	19	9	9	10	6	3	3	15	1357