Research Article
Predicting Disease Onset from Mutation Status Using Proband and Relative Data with Applications to Huntington's Disease
Table 5
Mean and standard deviation of the AAO estimated from the model (
2.1) for four analyses.
| | Langbehn | COHORT data | | data | Probands diagnosi | Probands sympto | Combined sympto |
| CAG | Mean | SD | Mean | SD | Mean | SD | Mean | SD |
| 41 | 57.06 | 10.50 | 59.84 | 8.78 | 57.74 | 9.13 | 59.33 | 11.68 | 43 | 48.06 | 8.62 | 51.17 | 7.31 | 49.32 | 7.90 | 50.63 | 9.60 | 46 | 38.66 | 7.08 | 41.29 | 5.97 | 39.66 | 6.57 | 41.20 | 7.59 | 48 | 34.32 | 6.57 | 36.31 | 5.47 | 34.75 | 5.95 | 36.69 | 6.79 | 50 | 31.08 | 6.28 | 32.32 | 5.16 | 30.80 | 5.50 | 33.21 | 6.28 |
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using proband age-at-diagnosis data; : using proband age-at-first-symptom data; : using proband and relative combined age-at-first-symptom data.
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