Research Article

A Two-Stage Penalized Logistic Regression Approach to Case-Control Genome-Wide Association Studies

Table 4

The simulated average PDR and FDR under Model 3: two-locus threshold interaction effects.

( 𝑛 , 𝑃 ) 𝜆 𝑞 PDRFDR
TPLR MT TPLR MT

(800,1000)  0.80.1 0.5300.455 0.0860.884
0.90.1 0.7300.695 0.0520.965
1.00.1 0.8100.840 0.0470.970

(800,5000)  0.80.1 0.3500.270 0.0280.800
0.90.1 0.6200.490 0.1010.999
1.00.1 0.7120.657 0.0600.982