Methods for Analyzing Multivariate Phenotypes in Genetic Association Studies

Table 1

Relationship between MANOVA test statistics and canonical correlation for association test of multivariate phenotype and a genetic marker.

MANOVA test	𝑓(𝜌̂)
Roy’s largest root	𝜌̂^2
Hotelling-Lawley trace	𝜌̂^2/1−𝜌̂^2
Wilks lambda	1−𝜌̂^2
Pillai-Bartlett trace	𝜌̂^2