Number of Patients per Cohort and Sample Size Considerations Using Dose Escalation with Overdose Control

<table>All the possible dose sequences that could be realized for the first four patients and a selected situation for patient 5. It assumes no simultaneous treatment of patients.</table>

Journal of Probability and Statistics

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Figure 3

Figure 3: Number of Patients per Cohort and Sample Size Considerations Using Dose Escalation with Overdose Control 