Research Article

Explorations of Unilateral Diaphragmatic Paralysis

Table 1

Results summary, according to diaphragmatic status, with on one side confirmed diaphragmatic paralysis, and on the other side normal diaphragm. value was calculated using Mann-Whitney nonparametric test between these two groups, and was significant for all presented variables, except Pes, sniff.

Age Paralysis side VC FEV1 FRC Pes, sniff Pes, mip Pdi, cms Pdi, ums (left) Pdi, ums (right)Paradox
(years)Left/right/no (% pred) (% pred) (% pred) (cmH2O) (cmH2O) (cmH2O) (cmH2O)(cmH2O)(y/n)

Patients with diaphragmatic paralysis
#158Right 28.5 25.1 # 42 32 8.0 6.0 5.0 y
#266Right 84.4 76.8 72.8 71 47 13.0 12.0 4.0 y
#365Right 100.0 100.0 100.0 54 69 10.6 7.4 4.0 y
#467Right 34.1 40.5 83.5 53 70 5.0 10.0 4.0 y
#571Right 71.3 60.5 143.8 60 44 10.0 5.0 0.0 n
#664Right 57.3 58.9 54.0 57 61 3.0 6.0 3.0 y
#746Left 106.6 93.8 88.8 100 85 13.0 8.0 20.0 n
#868Right 88.8 61.7 64.8 48 # 6.0 8.0 4.0 y
#962Left 85.1 86.0 68.2 65 69 18.0 9.0 19.0 n
#1072Left 115.8 117.3 93.5 110 82 20.0 6.0 6.0 n
#1175Right 106.7 89.7 95.0 71 63 20.0 11.0 8.0 n
#1274Right 92.5 75.3 109.5 72 72 17.7 9.6 7.1 n
#1359Left 70.7 75.9 50.1 70 74 18.0 4.0 5.0 y
#1452Right 79.6 80.2 67.4 71 89 13.0 6.0 8.0 y
#1556Left 73.0 70.1 178.8 91 69 21.0 8 8.0 n
Mean ± SE

Patients without diaphragmatic paralysis
#1651 No 107.2 97.3 106.0 92 90 34.0 19.0 15.0 n
#1738 No 95.5 90.0 104.2 75 75 32.0 18.3 19.9 n
#1832 No 96.4 93.8 88.7 116 91 25.0 25.0 23.0 n
#1974 No 92.3 95.8 98.0 67 53 23.0 13.0 12.0 n
#2041 No 107.8 102.3 92.5 80 122 36.0 19.0 16.0 n
#2142 No 99.3 100.0 114.1 84 # 29.0 18.0 13.0 n
#2244 No 87.4 89.6 115.4 61 73 18.0 15.0 16.0 n
Mean ± SE
value<0,010,050,010,10,080,05<0,01<0,01<0,01

VC: vital capacity.
FEV1: forced expiratory volume in one second.
FRC: functional residual capacity.
Pes, sniff: esophageal pressure during strong sniff.
Pes, mip: maximal esophageal inspiratory pressure.
Pdi, cms: transdiaphragmatic pressure induced by cervical bilateral phrenic nerve magnetic stimulation.
Pdi, ums: transdiaphragmatic pressure induced by unilateral phrenic nerve magnetic stimulation.