Instrument for Label-Free Detection of Noncoding RNAs

Figure 1

View inside temperature-controlled box containing the cantilever instrument. Laser ray path visible due to slight haze. (1, 2, 3) x, y, z positioning; (4) parallel alignment of fibers to cantilevers; (5) longitudinal focusing on cantilevers; (6) optical fibers (laser sources); (7) lens; (8) flow chamber (holds cantilever array chip); (9) tubing to syringe pump; (10) mirror with tilt function; (11) position-sensitive detector (PSD); (12) PSD alignment; (13) camera module; (14) ground plate connected to flow cycle thermostat; (15) thermal insulated box; (16) inset of cantilever array image mounted in flow chamber (8) taken with the camera module (13); (i) and (ii) illustrate the two temperature-controlled zones.