Histopathological Variants of Cutaneous Squamous Cell Carcinoma: A Review
Figure 1
Actinic keratosis (AK). (a) One of the first clues to the diagnosis of AK at scanning magnification is the discontinuity of the parakeratosis as the dysplastic process spares adnexal structures. Note the lack of parakeratosis over the sebaceous gland. This specimen also demonstrates dense dermal elastosis (40x). (b) Example of an early AK with keratinocyte dysplasia confined to the lower third of the epidermis (200x). (c) A more established lesion of AK demonstrating nearly full thickness keratinocyte dysplasia and prominent budding of the basal layer into the superficial dermis (200x).
