Adjuvant Therapy: Melanoma

Table 3

Phase II/III studies of chemotherapeutic agents in melanoma.

Study reference	No. of patients eligible for analysis (followup)	TNM stage	Treatment arm	Median followup at time of reporting (yrs)	OS
Veronesi et al. 1982 [96]	931	II/III	DTIC; BCG; DTIC + BCG; Obs	5	NS
Lejeune et al. 1988 [97]	325	I, IIA, IIB	DTIC; Levamisole placebo	4	NS
Fisher et al. 1981 [98]	181	II/III	CCNU; Obs	3	NS
Koops et al. 1998 [99]	632	II/III	Isolated limb perfusion + hyperthermia; Obs	6.4	BS

Keys: NS—not significant; S—significant; HR—hazard ratio.