Pigmentation, Melanocyte Colonization, and p53 Status in Basal Cell Carcinoma

Table 1

Clinical, microscopic, immunohistologic, and sequencing data of the basal cell carcinomas analysed in this study.

Gender	Localization	Growth pattern	Macroscopic pigmentation	Melanin	Melan-A	p53 expression	p53 sequencing
m	Nose	Micronodular	No	0%	10%	60%
f	Nose	Morpheaform	No	0%	7%	75%
m	Forearm	Nodular	Yes	80%	27%	1%
m	Nose	Micronodular	Yes	20%	15%	0%
f	Lower leg	Superficial	No	0%	5%	90%
f	Chin	Superficial	No	3%	3%	7%
m	Cheek	Nodular	No	0%	15%	3%
m	Temple	Nodular	No	0%	3%	50%
m	Neck	Nodular	No	0%	10%	5%
m	Cheek	Infiltrative	No	0%	10%	1%
m	Nose	Nodular	No	0%	10%	3%
m	Forehead	Morpheaform	No	0%	2%	3%
f	Nose	Nodular	No	0%	15%	0%
m	Breast	Nodular	No	0%	3%	0%	wt
m	Temple	Superficial	No	0%	7%	75%
f	Periorbital	Nodular	No	0%	10%	0%
m	Back	Nodular	No	0%	15%	0%
m	Shoulder	Superficial	No	0%	7%	3%
m	Neck	Nodular	No	0%	10%	25%
f	Cheek	Superficial	No	0%	3%	0%	wt
m	Scapula	Nodular	Yes	15%	15%	5%	g605a 202H
m	Cheek	Nodular	Yes	10%	10%	95%	g743a 248A
m	Forehead	Nodular	No	0%	3%	3%
m	Scalp	Superficial	Yes	7%	17%	10%	wt
f	Shoulder	Infiltrative	Yes	7%	7%	0%
m	Sternum	Infiltrative	No	0%	2%	0%
m	Sternum	Micronodular	No	0%	3%	60%
m	Nose	Infiltrative	No	0%	5%	25%
f	Shoulder	Micronodular	Yes	5%	7%	75%	c844g 282G
m	Forehead	Micronodular	No	0%	5%	45%
m	Temple	Morpheaform	No	0%	7%	50%
f	Forehead	Morpheaform	No	0%	3%	0%
m	Cheek	Micronodular	No	0%	15%	0%
f	Cheek	Morpheaform	No	0%	3%	0%	wt
f	Nose	Micronodular	No	10%	5%	0%
m	Nose	Micronodular	No	0%	10%	0%
f	Nose	Morpheaform	No	0%	3%	80%
m	Temple	Infiltrative	No	0%	15%	75%
m	Occipital	Morpheaform	No	0%	3%	0%	wt
m	occipital	Morpheaform	No	0%	3%	0%
m	Arm	Nodular	Yes	5%	15%	7%
m	Breast	Nodular	Yes	5%	10%	20%
f	Chest	Superficial	Yes	7%	10%	90%	c380t S127F
m	Neck	Nodular	Yes	5%	7%	15%
f	Breast	Superficial	Yes	5%	15%	75%	wt
f	Sternum	Superficial	Yes	5%	5%	10%
f	Hip	Superficial	Yes	10%	10%	35%
m	Forehead	Superficial	Yes	10%	10%	95%
m	Back	Superficial	Yes	3%	7%	7%

m: male; f: female; Melanin, melan-A and p53 expression were assessed by immunohistochemistry; sequencing of the p53 gene was performed for the exons 4-8;