Case Report

Pigmented Nodular Basal Cell Carcinomas in Differential Diagnosis with Nodular Melanomas: Confocal Microscopy as a Reliable Tool for In Vivo Histologic Diagnosis

Figure 1

(a) Dermoscopic image of nodular pigmented lesion showing a blue gray veil structureless brown areas and dark brown dots in the center (original magnification 30 ). (b) RCM image (  mm) at dermoepidermal level, showing a general cauliflower architecture highly specific for BCC diagnosis (scale bar: 500  m). (c) RCM image (  mm, white frame), showing dark silhouettes (yellow arrows) outlined by dark spaces. In the inner portion of them, bright filaments were present (white arrows) (scale bar: 50  m). (d) Histology showing basaloid nodules in the dermis corresponding to hypopigmented dark silhouettes. Within and outside the tumor nests some melanin was present (H&E section; original magnification 100).
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