Pigmented Nodular Basal Cell Carcinomas in Differential Diagnosis with Nodular Melanomas: Confocal Microscopy as a Reliable Tool for In Vivo Histologic Diagnosis
Figure 4
(a) Dermoscopy showed structureless areas with blue hue and a globular pattern. Ulceration was present in the center of the nodule (original magnification 30). (b) RCM image ( mm) at dermal level, showing pleomorphic small cells (yellow arrow) arranged to form a cerebriform nests delimitated by fibrous septa (scale bar: 50 m). (c) RCM image ( mm) at dermal level, showing an enlarged new-born vessel with a prominent blood flow (yellow arrow) (scale bar: 50 m). (d) Histology showing a solid proliferation of atypical melanocytes in which new-born vessels can be recognized (H&E section; original magnification 100).