Review Article

Deciphering Squamous Cell Carcinoma Using Multidimensional Genomic Approaches

Figure 1

Mechanisms of DNA copy number alteration. (a) Segmental gains and losses can lead to DNA copy number alterations. (b) Allelic imbalance and loss of heterozygosity (LOH) can arise from a deletion event or gene conversion during mitosis.
541405.fig.001a
(a)
541405.fig.001b
(b)