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Journal of Skin Cancer
Volume 2012 (2012), Article ID 741397, 5 pages
http://dx.doi.org/10.1155/2012/741397
Clinical Study

Basal Cell Carcinoma in Asians: A Retrospective Analysis of Ten Patients

1School of Medicine, Indiana University, Indianapolis, IN 46202-3082, USA
2School of Medicine, University of California at Los Angeles, Los Angeles, CA 90095, USA

Received 31 March 2012; Accepted 10 May 2012

Academic Editor: M. Lebwohl

Copyright © 2012 Michael G. Moore and Richard G. Bennett. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Few studies have been done that characterize basal cell carcinoma (BCC) in Asians because this tumor is relatively uncommon in this population group. Objective. To characterize BCC in Asians. Methods. We retrospectively examined fifteen patient variables and eight tumor variables of ten Asian patients with BCC and compared these results to those of thirty matched Caucasian controls with BCC. Results. Asians developed their first BCC at an older age than the age of first BCC in Caucasian controls (68.9 years versus 58.3 years; 𝑃 < 0 . 0 5 ). During their lifetime, Asians had fewer BCCs than the number of BCCs in Caucasian controls (1.11 versus 5.41; 𝑃 < 0 . 0 2 ), despite a similar estimated lifetime daily sun exposure (hours/day) for both groups. Compared to BCCs in Caucasian controls, a higher percentage of BCCs in Asians were clinically pigmented (50.0% versus 3.3%; 𝑃 < 0 . 0 1 ). Conclusion. Asians develop BCCs later in life and develop fewer BCCs over their lifetime than Caucasians, despite similar estimated lifetime daily sun exposure. This finding is probably due to skin pigmentation in Asians being more protective of ultraviolet light than skin pigmentation in Caucasians.