- About this Journal ·
- Abstracting and Indexing ·
- Advance Access ·
- Aims and Scope ·
- Article Processing Charges ·
- Articles in Press ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
Journal of Skin Cancer
Volume 2012 (2012), Article ID 914267, 7 pages
Diagnostic Role of Chromosomal Instability in Melanoma
Department of Dermatology, Anna Fund Melanoma Program, Sylvester Comprehensive Cancer Center and Interdisciplinary Stem Cell Institute, Miller School of Medicine, University of Miami, Room 912, 1501 NW 10th Avenue, Miami, FL 33136-1012, USA
Received 29 June 2012; Revised 20 September 2012; Accepted 21 September 2012
Academic Editor: Lionel Larue
Copyright © 2012 Nitika Dabas et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- E. R. Farmer, R. Gonin, and M. P. Hanna, “Discordance in the histopathologic diagnosis of melanoma and melanocytic nevi between expert pathologists,” Human Pathology, vol. 27, no. 6, pp. 528–531, 1996.
- B. A. Shoo, R. W. Sagebiel, and M. Kashani-Sabet, “Discordance in the histopathologic diagnosis of melanoma at a melanoma referral center,” Journal of the American Academy of Dermatology, vol. 62, no. 5, pp. 751–756, 2010.
- S. Lodha, S. Saggar, J. T. Celebi, and D. N. Silvers, “Discordance in the histopathologic diagnosis of difficult melanocytic neoplasms in the clinical setting,” Journal of Cutaneous Pathology, vol. 35, no. 4, pp. 349–352, 2008.
- K. C. Veenhuizen, P. E. De Wit, W. J. Mooi, et al., “Quality assessment by expert opinion in melanoma pathology: experience of the pathology panel of the Dutch Melanoma Working Party,” Journal of Pathology, vol. 182, no. 3, pp. 266–272, 1997.
- E. B. Hawryluk, A. J. Sober, A. Piris, et al., “Histologically challenging melanocytic tumors referred to a tertiary care pigmented lesion clinic,” Journal of the American Academy Dermatology, vol. 67, no. 4, pp. 727–735, 2012.
- P. Gerami, S. S. Jewell, and L. E. Morrison, “Fluorescence in situ hybridization (FISH) as an ancillary diagnostic tool in the diagnosis of melanoma,” American Journal of Surgical Pathology, vol. 33, no. 8, pp. 61146–61156, 2009.
- C. Curiel-Lewandrowski, C. C. Kim, S. M. Swetter, et al., “Survival is not the only valuable end point in melanoma screening. Melanoma Prevention Working Group Pigmented Skin Lesion Sub-Committee,” Journal of Investigative Dermatology, vol. 132, no. 5, pp. 1332–1337, 2012.
- B. C. Bastian, A. B. Olshen, P. E. LeBoit, and D. Pinkel, “Classifying melanocytic tumors based on DNA copy number changes,” American Journal of Pathology, vol. 163, no. 5, pp. 1765–1770, 2003.
- C. R. Boland, N. L. Komarova, and A. Goel, “Chromosomal instability and cancer: not just one CINgle mechanism,” Gut, vol. 58, no. 2, pp. 163–164, 2009.
- S. Negrini, V. G. Gorgoulis, and T. D. Halazonetis, “Genomic instability an evolving hallmark of cancer,” Nature Reviews Molecular Cell Biology, vol. 11, no. 3, pp. 220–228, 2010.
- D. Gordon, B. Resio, D. Pellman, et al., “Causes and consequences of aneuploidy in cancer,” Nature Reviews Genetics, vol. 13, no. 3, pp. 189–203, 2012.
- S. F. Bakhoum and D. A. Compton, “Chromosomal instability and cancer: a complex relationship with therapeutic potential,” Journal Clinical Investigation, vol. 122, no. 4, pp. 1138–1143, 2012.
- Y. B. Yurov, S. G. Vorsanova, and I. Y. Iourov, “GIN“n”CIN hypothesis of brain aging: deciphering the role of somatic genetic instabilities and neural aneuploidy during ontogeny,” Molecular Cytogenetics, vol. 2, no. 23, pp. 1–9, 2009.
- A. L. Ross, D. E. Leder, J. Weiss, J. Izakovic, and J. M. Grichnik, “Genomic instability in cultured stem cells: associated risks and underlying mechanisms,” Regenerative Medicine, vol. 6, no. 5, pp. 653–662, 2011.
- J. Bauer and B. C. Bastian, “Distinguishing melanocytic nevi from melanoma by DNA copy number changes: comparative genomic hybridization as a research and diagnostic tool,” Dermatologic Therapy, vol. 19, no. 1, pp. 40–49, 2006.
- E. Wang, S. Voiculescu, I. C. Le Poole et al., “Clonal persistence and evolution during a decade of recurrent melanoma,” Journal of Investigative Dermatology, vol. 126, no. 6, pp. 1372–1377, 2006.
- J. M. Grichnik, “Genomic instability and tumor stem cells,” Journal of Investigative Dermatology, vol. 126, no. 6, pp. 1214–1216, 2006.
- M. Sabatino, Y. Zhao, S. Voiculescu et al., “Conservation of genetic alterations in recurrent melanoma supports the melanoma stem cell hypothesis,” Cancer Research, vol. 68, no. 1, pp. 122–131, 2008.
- B. C. Bastian, “Understanding the progression of melanocytic neoplasia using genomic analysis: from fields to cancer,” Oncogene, vol. 22, no. 20, pp. 3081–3086, 2003.
- J. Draeger, H. Schell, F. Kiesewetter, T. Liehr, and E. Gebhart, “Chromosome gain and loss in paraffin sections from malignant melanomas of the skin,” International Journal of Oncology, vol. 10, no. 1, pp. 89–92, 1997.
- B. C. Bastian, P. E. LeBoit, and D. Pinkel, “Mutations and copy number increase of HRAS in Spitz nevi with distinctive histopathological features,” American Journal of Pathology, vol. 157, no. 3, pp. 967–972, 2000.
- V. Martin, S. Banfi, A. Bordoni, et al., “Presence of cytogenetic abnormalities in Spitz naevi: a diagnostic challenge for fluorescence in-situ hybridization analysis,” Histopathology, vol. 60, no. 2, pp. 336–346, 2012.
- J. A. Curtin, J. Fridlyand, T. Kageshita et al., “Distinct sets of genetic alterations in melanoma,” The New England Journal of Medicine, vol. 353, no. 20, pp. 2135–2147, 2005.
- J. A. Curtin, K. Busam, D. Pinkel, and B. C. Bastian, “Somatic activation of KIT in distinct subtypes of melanoma,” Journal of Clinical Oncology, vol. 24, no. 26, pp. 4340–4346, 2006.
- J. M. Grichnik, J. A. Burch, J. Burchette, and C. R. Shea, “The SCF/KIT pathway plays a critical role in the control of normal human melanocyte homeostasis,” Journal of Investigative Dermatology, vol. 111, no. 2, pp. 233–238, 1998.
- L. Casorzo, C. Luzzi, A. Nardacchione, F. Picciotto, A. Pisacane, and M. Risio, “Fluorescence in situ hybridization (FISH) evaluation of chromosomes 6, 7, 9 and 10 throughout human melanocytic tumorigenesis,” Melanoma Research, vol. 15, no. 3, pp. 155–160, 2005.
- G. V. Wettengel, J. Draeger, F. Kiesewetter, H. Schell, S. Neubauer, and E. Gebhart, “Differentiation between Spitz nevi and malignant melanomas by interphase fluorescence in situ hybridization,” International Journal of Oncology, vol. 14, no. 6, pp. 1177–1183, 1999.
- M. Döbler, J. Schuh, F. Kiesewetter, H. Schell, T. Liehr, and E. Gebhart, “Deletion monitoring in skin tumors by interphase-FISH using band-specific DNA probes,” International Journal of Oncology, vol. 14, no. 3, pp. 571–576, 1999.
- P. Gerami and A. Zembowicz, “Update on fluorescence in situ hybridization in melanoma: state of the art,” Archives of Pathology and Laboratory Medicine, vol. 135, no. 7, pp. 830–837, 2011.
- D. Hossain, J. Qian, J. Adupe, et al., “Differentiation of melanoma and benign nevi by fluorescence in-situ hybridization,” Melanoma Research, vol. 21, no. 5, pp. 426–430, 2011.
- Y. Fang, S. Dusza, S. Jhanwar, et al., “Fluorescence In Situ hybridization (FISH) analysis of melanocytic nevi and melanomas: sensitivity, specificity, and lack of association with sentinel node status,” International Journal of Surgical Pathology, vol. 20, no. 5, pp. 434–440, 2012.
- B. Vergier, M. Prochazkova-Carlotti, A. De La Fouchardière et al., “Fluorescence in situ hybridization, a diagnostic aid in ambiguous melanocytic tumors: European study of 113 cases,” Modern Pathology, vol. 24, no. 5, pp. 613–623, 2011.
- A. Abásolo, M. T. Vargas, J. J. Ríos-Martín, et al., “Application of fluorescence in situ hybridization as a diagnostic tool in melanocytic lesions, using paraffin wax-embedded tissues and imprint-cytology specimens,” Clinical and Experimental Dermatology. In press.
- T. Gaiser, H. Kutzner, G. Palmedo et al., “Classifying ambiguous melanocytic lesions with FISH and correlation with clinical long-term follow up,” Modern Pathology, vol. 23, no. 3, pp. 413–419, 2010.
- P. Gerami, G. Li, P. Pouryazdanparast, et al., “A highly specific and discriminatory FISH assay for distinguishing between benign and malignant melanocytic neoplasms,” The American Journal of Surgical Pathology, vol. 36, no. 6, pp. 808–817, 2012.
- S. Satoh, T. Hashimoto-Tamaoki, J. Furuyama, K. Mihara, M. Namba, and Y. Kitano, “High frequency of tetraploidy detected in malignant melanoma of Japanese patients by fluorescence in situ hybridization,” International Journal of Oncology, vol. 17, no. 4, pp. 707–715, 2000.
- P. Gerami, A. Wass, M. Mafee, Y. Fang, M. P. Pulitzer, and K. J. Busam, “Fluorescence in situ hybridization for distinguishing nevoid melanomas from mitotically active nevi,” American Journal of Surgical Pathology, vol. 33, no. 12, pp. 1783–1788, 2009.
- M. Roh, O. E. Franco, S. W. Hayward, R. van der Meer, and S. A. Abdulkadir, “A role for polyploidy in the tumorigenicity of Pim-1-expressing human prostate and mammary epithelial cells,” PLoS ONE, vol. 3, no. 7, Article ID e2572, 2008.
- L. Lv, T. Zhang, Q. Yi, et al., “Tetraploid cells from cytokinesis failure induce aneuploidy and spontaneous transformation of mouse ovarian surface epithelial cells,” Cell Cycle, vol. 11, no. 15, pp. 2864–2875, 2012.
- T. van den Bosch, J. G. van Beek, J. Vaarwater, et al., “Higher percentage of FISH-determined monosomy 3 and 8q amplification in uveal melanoma cells relate to poor patient prognosis,” Investigative Ophthalmology & Visual Science, vol. 53, no. 6, pp. 2668–2674, 2012.
- K. A. Patel, N. D. Edmondson, F. Talbot, M. A. Parsons, I. G. Rennie, and K. Sisley, “Prediction of prognosis in patients with uveal melanoma using fluorescence in situ hybridisation,” British Journal of Ophthalmology, vol. 85, no. 12, pp. 1440–1444, 2001.
- A. Jemal, R. Siegel, J. Xu, and E. Ward, “Cancer statistics, 2010,” CA Cancer Journal for Clinicians, vol. 60, no. 5, pp. 277–300, 2010.
- R. Siegel, D. Naishadham, and A. Jemal, “Cancer statistics, 2010,” CA A Cancer Journal for Clinicians, vol. 62, no. 1, pp. 10–29, 2012.