Table 2: Clinical and histopathological characteristics of patients with cutaneous melanoma in the western region of Santa Catarina, Brazil, classified by gender.

Characteristics (n)MenWomenP

Age (497) 5 0 . 4 5 ± 1 5 . 2 0 5 0 . 8 1 ± 1 5 . 5 7 0.045**
Site (489)<0.001*
Head and neck36 (17.82)55 (19.16)
Trunk73 (36.14)55 (19.16)
Members76 (37.62)164 (57.14)
Unknown17 (8.42)13 (4.54)
Histological type (445)0.04*
SSM104 (59.10)183 (68.03)
NM42 (23.86)48 (17.84)
LMM13 (7.39)20 (7.43)
MAL8 (4.54)9 (3.35)
Other9 (5.11)9 (3.35)
Tumor thickness (mm) (462)<0.01*
≤1 mm73 (39.46)135 (48.74)
1.01–2.029 (15.67)54 (19.49)
2.01–4.028 (15.14)49 (17.69)
>4.055 (29.73)39 (14.08)
Clark (420)<0.01*
I26 (15.76)29 (11.37)
II16 (9.70)42 (16.47)
III33 (20)78 (30.59)
IV72 (43.64)100 (39.22)
V18 (10.90)6 (2.35)
Presence of ulceration (418) 0.013*
Yes67 (41.61)78 (30.35)
No94 (58.39)179 (69.65)
Presence of regression (399)0.254*
Yes37 (24.02)49 (20.00)
No117 (75.98)196 (80.00)
Mitotic index (mitoses/mm2) (401)0.045*
027 (17.65)49 (19.76)
≥1126 (82.35)199 (80.24)
SLN positive (225)0.600*
Yes21 (24.70)16 (11.42)
No64 (72.30)124 (88.57)
Growth phase (434)0.271*
Radial28 (16.57)49 (18.49)
Vertical141 (83.43)216 (81.51)
Vascular invasion (400)0.877*
Yes16 (10.19)24 (9.88)
No141 (89.81)219 (90.12)
Perineural invasion (392)0.398*
Yes6 (3.82)4 (1.70)
No151 (96.18)231 (98.30)

Data presented as mean ± SD and frequency (percentage). **Student’s t-test * Chi-square test. SSM, superficial spreading melanoma; NM, nodular melanoma; LMM, lentigo maligna melanoma; MAL, acrolentiginous melanoma; SLN, sentinel lymph node.