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Journal of Skin Cancer
Volume 2012 (2012), Article ID 981308, 13 pages
http://dx.doi.org/10.1155/2012/981308
Research Article

Genome-Wide Analysis of Gene and Protein Expression of Dysplastic Naevus Cells

1Department of Dermatology, Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, The Netherlands
2Department of Parasitology, Leiden University Medical Center, Albinusdreef 2, 2300 RC Leiden, The Netherlands
3Center for Human and Clinical Genetics, Leiden University Medical Center, Albinusdreef 2, 2300 RC Leiden, The Netherlands

Received 9 August 2012; Revised 10 October 2012; Accepted 11 October 2012

Academic Editor: Lionel Larue

Copyright © 2012 Linda Gao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Melanocytes derived from dysplastic naevus (DNMC) and normal adjacent skin (MC) of 18 different patients were subjected to mass spectrometry analysis in order to find proteins that were differentially expressed between both melanocyte sample groups. Mass fingerprint and MS/MS data were searched against the human protein database and resulted in the annotation of 70 proteins.

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