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Figure 1: Imaging of patients with 188Re-6D2 mAb. (a) Whole-body scintigraphic image of a patient from Phase Ia showing absence of 188Re-6D2 uptake in normal melanized tissues: from left to right—0.4, 3, 5, and 20 hr images; (b) patient from Phase Ia study with mediastinal and lung metastases: top panel—18FDG PET/CT 10 days before the study, lower panels—SPECT/CT of 188Re-6D2 mAb at 2, 8, and 24 hrs after injection, respectively; (c) patient from Phase Ia study with large pelvic mass: from left to right—18FDG PET/CT 10 days before the study, SPECT/CT of 188Re-6D2 mAb 8 hrs after injection.