Simultaneous Determination of Prasugrel and Aspirin by Second Order and Ratio First Order Derivative Ultraviolet Spectrophotometry

Table 3

(a) Recovery studies for Prasugrel. (b) Recovery studies for Aspirin.

(a)

% level	Amount of PRA (mg)	Amount of ASP (mg)	Amount of standard PRA added (mg)	Amount of standard ASP added (mg)	Method D2; (𝑛=3)	Method RD1; (𝑛=3)
					% recovery of PRA; (mean% ± SD)	% recovery of PRA; (mean% ± SD)
80%	10	75	8	0	99.70%±2.57%	100.75%±1.01%
100%	10	75	10	0	98.81%±2.06%	100.07%±1.28%
120%	10	75	12	0	100.19%±1.71%	100.46%±0.68%

(b)

% level	Amount of PRA (mg)	Amount of ASP (mg)	Amount of standard PRA added (mg)	Amount of standard ASP added (mg)	Method D2; (𝑛=3)	Method RD1; (𝑛=3)
					% recovery of ASP; (mean% ± SD)	% recovery of ASP; (mean% ± SD)
80%	10	75	0	60	99.53%±1.14%	101.60%±0.27%
100%	10	75	0	75	100.04%±0.69%	100.92%±0.78%
120%	10	75	0	90	99.87%±1.89%	99.48%±0.58%