Research Article
Simple Spectrophotometric Methods for Determination of Tenofovir Fumarate and Emtricitabine in Bulk Powder and in Tablets
Table 2
Accuracy and precision of the proposed spectrophotometric methods for analysis of TEN and EMT.
|
Analyte |
Nominal value (g mL−1) | Within-day () | Between-day () | Found ± SD (g mL−1) | RSD (%) | Er (%) | Found ± SD (g mL−1) | RSD (%) | Er (%) |
| TEN (1DR) | 4.0 | | 0.932 | −1.801 | | 0.798 | −1.407 | 8.0 | | 0.461 | −1.398 | | 0.802 | −1.852 | 20.0 | | 0.692 | −0.513 | | 0.559 | −0.695 |
| EMT (1D) | 0.5 | | 0.668 | −1.890 | | 1.320 | −0.756 | 8.0 | | 0.825 | −0.732 | | 1.028 | −0.543 | 40.0 | | 0.328 | −0.269 | | 0.815 | 0.039 |
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