Interaction between Chromosomal Protein HMGB1 and DNA Studied by DNA-Melting Analysis

Figure 2

The first derivative of the melting curves of DNA in the complexes with HMGB1 at different protein to DNA ratios (w/w): ■: (DNA); ∆: ; ◆: ; ▿: ; ●: . All curves were obtained in 0.25 mM EDTA/0.2 mM NaCl solution.