Liquid Chromatography-Tandem Mass Spectrometric Assay for Determination of Stavudine in Human Plasma

Table 3

The main pharmacokinetic parameters.

Parameter	Reference	Test	90% confidence interval (%)
AUC0--𝑡  (ng·h/mL)	872±228	914±284	98.6–109.8
AUC0--∞ (ng·h/mL)	889±228	931±287
𝐶max  (ng/mL)	480±151	574±178	97.8–125.1
𝑇max  (h)	0.55±0.19	0.54±0.20
𝑘𝑒  (h^−1)	0.42±0.09	0.42±0.07
𝑡1/2  (h)	1.72±0.43	1.68±0.29
𝐹 (%)		105.0±13.6