Fourier Transform Infrared Spectroscopic Imaging of Fracture Healing in the Normal Mouse

Figure 5

Quantitative results of FTIRI of the various callus tissues and cortical bone at different time-points. Each value represents the mean of 6 to 8 bone specimens of equivalent tissue type and time point (CC: ). (a) Mineral/matrix ratio; (b) carbonate/phosphate ratio; (c) hydroxyapatite crystallinity; (d) acid phosphate substitution into hydroxyapatite. (e) Collagen maturity. CO = cortical bone; WB = woven bone; IM = area of intramembranous new bone formation; EC = area of endochondral new bone formation; CC = early calcified cartilage.

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