Table 4:
Contribution of cathepsin L or B on bone resorption.
Inhibitors (10
-6
M)
Cathepsin L
Cathepsin B
Bone resorption
Control
100
100
100
%
Pepstatin
−
103
104
104
%
CA-074
−
100
2.2
94
%
E-64
+
10
2
40
%
Cystatin
α
+
3.1
4.3
18
%
Chymostatin
+
9.8
101
6
%
CA-148
+
0
100
0
%