Journal of Signal Transduction / 2011 / Article / Tab 3 / Review Article
Fish Suppressors of Cytokine Signaling (SOCS): Gene Discovery, Modulation of Expression and Function Table 3 Amino acid identities (top right) and similarities (bottom left) of the fish SOCS5a and 5b molecules and SOCS5 molecules from birds, amphibians, and mammals. The accession numbers of the protein sequences are given in Figure
3 .
aa 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 1. Zebrafish-a1 557 62.8 76.3 76.3 76.6 75.0 42.7 43.2 43.3 43.0 41.3 41.9 64.1 64.0 64.6 63.1 60.2 2. Zebrafish-a2 528 76.1 64.8 66.3 64.4 64.2 44.5 42.9 43.1 42.7 43.3 42.4 63.1 63.1 62.5 62.2 60.1 3. Stickleback-a 561 84.5 75.6 87.4 86.4 84.8 42.3 43.6 42.4 43.9 41.9 43.2 65.4 65.4 65.9 63.9 62.4 4. Medaka-a 561 84.5 76.3 91.1 83.2 82.8 43.3 42.0 42.5 44.4 43.5 42.1 64.4 64.6 66.3 65.1 62.3 5. Tetraodon-a 559 83.5 75.3 90.4 87.9 90.5 42.5 42.4 44.1 43.1 40.7 42.4 63.4 63.6 65.2 63.8 61.5 6. Fugu-a 550 83.8 76.4 89.1 88.1 93.7 43.0 43.0 43.3 43.7 41.4 43.5 61.5 62.0 63.6 63.2 61.4 7. Zebrafish-b 497 57.5 59.7 56.7 55.8 57.4 57.3 63.7 63.5 61.5 61.6 61.2 44.5 44.8 45.6 44.4 44.8 8. Trout-b 544 60.7 60.7 59.0 59.5 58.5 59.1 75.0 74.4 75.0 71.5 72.1 43.9 44.9 45.4 43.9 42.8 9. Stickleback-b 533 60.7 59.5 57.8 58.1 60.5 59.3 76.4 81.6 76.5 73.1 73.3 45.4 45.7 44.3 45.4 44.1 10. Medaka-b 544 60.9 59.0 59.4 59.4 58.1 59.1 74.3 84.9 84.2 74.6 73.7 45.5 47.1 45.8 46.2 45.3 11. Tetraodon-b 542 59.8 59.8 57.8 59.5 56.4 58.4 72.7 80.7 80.1 82.4 88.2 44.5 45.6 46.1 44.1 42.1 12. Fugu-b 537 59.2 59.0 59.2 58.5 57.6 59.6 72.6 81.6 81.4 82.0 90.8 44.2 44.6 44.9 43.6 43.8 13. Human 536 76.1 75.4 75.2 74.7 75.1 75.1 58.8 61.4 63.4 63.1 61.4 62.2 97.8 94.6 91.0 80.6 14. Cow 536 75.8 75.6 75.4 74.9 74.8 75.5 59.3 61.6 62.3 63.2 61.6 62.2 99.1 95.0 90.9 80.1 15. Mouse 536 76.5 75.9 75.6 75.0 75.1 76.2 60.8 61.8 63.2 63.8 61.8 62.6 97.2 97.8 89.4 79.0 16. Chicken 536 74.3 75.6 74.7 74.3 75.3 76.2 58.6 61.2 61.2 63.1 60.9 61.8 95.1 94.8 94.4 79.7 17. Frog 535 74.7 75.5 74.2 74.9 74.1 75.6 59.3 60.1 63.6 61.6 60.3 62.2 90.1 89.6 89.2 88.8