The Roles of Mitogen-Activated Protein Kinase Pathways in TGF-β-Induced Epithelial-Mesenchymal Transition

Figure 1

The network of the mitogen-activated protein kinase (MAPK) family. Extracellular stimuli transduce signals to the nucleus. The sequential phosphorylation of MAPKKK, MAPKK, and MAPK activates their nuclear targets, kinases, and transcription factors. For details, refer to the text.