Functional Mechanisms and Roles of Adaptor Proteins in Abl-Regulated Cytoskeletal Actin Dynamics

Figure 5

Differential roles of Abi and Crk in signaling pathways of Abl-mediated actin dynamics. Upstream and downstream signaling cascades of Abl-mediated actin dynamics are schematically illustrated (solid arrow). Downstream signaling pathways unique to each member of the Abi and Crk families are also shown together with the respective outcomes (broken arrow).