Review Article

Pivotal Role of AKAP12 in the Regulation of Cellular Adhesion Dynamics: Control of Cytoskeletal Architecture, Cell Migration, and Mitogenic Signaling

Figure 2

AKAP12-null cells exhibit robust stress fiber formation as well as upregulated focal adhesion complexes. Wild type and AKAP12-null mouse embryonic fibroblasts were stained with either rhodamine-phalloidin (F-actin, (a) and (b)) or antivinculin antibody ((c) and (d)) followed by Alexa488 antibody. Scale bar, 10 μm.
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(a)
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(b)
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(c)
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(d)