Review Article
Nucleic Acids in Human Glioma Treatment: Innovative Approaches and Recent Results
Table 3
Strategies for siRNA delivery across the BBB.
| Delivery system | siRNA target | Ref. |
| Pegylated immunoliposomes | EGFR | [29] | siRNA/TfR antibody complexes by biotin-streptavidin bridge | Luciferase | [65] | Polyethylenimine/siRNA complexes | Pleiotrophin | [66] | Nanoparticles/siRNA complexes | HIF-1α | [68] | Recombinant adeno-associated virus | Hec1 | [69] | Herpes simplex virus 1 | EGFR; Rad51 | [70, 71] | Lentiviral vectors | shBcl-2 and S-TRAIL | [73] |
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