Clinical Spectrum of Oral Secondary Syphilis in HIV-Infected Patients

Table 1

Clinical characteristics in 20 patients with oral syphilis.

Characteristics	𝑛 (% )
AIDS^a	10 (50.0)
On HAART	14 (70.0)
Tobacco consumption (𝑛=19)	6 (31.6)
Alcohol consumption (𝑛=19)	4 (21.1)
Main type of lesion
Mucous patches	17 (85.5)
Shallow ulcers	2 (10.0)
Macular lesions	1 (5.0)
Oral site of main lesion^b
Soft palate-pillars	8 (40.0)
Hard palate	3 (15.0)
Tongue	3 (15.0)
Hard-soft palate-pillars	2 (10.0)
Hard-soft palate-tongue	1 (5.0)
Hard-soft palate-tongue-buccal mucosa	1 (5.0)
Upper labial mucosa	1 (5.0)
Gingiva	1 (5.0)
Minor type of lesion (𝑛=10)
Papular lesions	4 (40.0)
Macular lesions	4 (40.0)
Shallow ulcers	2 (20.0)
Oral site of minor lesion (𝑛=10)
Tongue	5 (50.0)
Hard palate	3 (30.0)
Gingiva/labial mucosa	1 (10.0)
Soft palate	1 (10.0)
Median antiretroviral use (range) months; (𝑛=14)	32.5 (1–134)
With undetectable viral load (<399 copies/mL) (𝑛=19)	10 (52.6)
Current median CD4^+ count (range) cells/μL (𝑛=19)	372 (44–734)

^a CD4⁺ T-lymphocyte count of <200 cells/μL (or <14 percentage) and/or documentation of an AIDS-defining condition (A3, B3, C1–3) [37]. ^bMain oral lesion was the most evident and florid oral manifestation.