Prevalence and Risk Factors of Mortality among Adult HIV Patients Initiating ART in Rural Setting of HIV Care and Treatment Services in North Western Tanzania: A Retrospective Cohort Study
Table 2
Univariate and multivariate analysis for factors associated with mortality among 740 participants while receiving ART.
Variables
Deaths while receiving ART
Unadjusted
Adjusted
No
Yes
OR (95% CI)
value
OR (95% CI)
value
Sex
Male
231 (35.3)
44 (51.2)
Female
423 (64.7)
42 (48.8)
1.9 (1.2–3.0)
0.005
1.8 (1.1–3.0)
0.015
Age
≥45 years
141 (21.6)
15 (17.4)
<45 years
513 (78.4)
71 (82.6)
0.8 (0.4–1.4)
0.380
Marital status
Married
248 (37.9)
35 (40.7)
1.2 (0.7–1.8)
0.618
Divorced
129 (19.7)
31 (36.1)
2.3 (1.4–3.7)
0.001
2.7 (1.6–4.7)
<0.001
Widow
169 (25.8)
18 (20.9)
0.8 (0.4–1.3)
0.326
Single
108 (16.6)
02 (02.3)
0.1 (0.0–0.5)
0.003
WHO stage
3 & 4
123 (32.6)
48 (55.8)
1 & 2
441 (67.4)
38 (44.2)
2.6 (1.7–4.1)
<0.001
2.3 (1.0–5.5)
0.05
Baseline TB
Yes
157 (24.1)
40 (46.5)
No
497 (75.9)
46 (53.5)
2.8 (1.7–4.4)
<0.001
1.0 (0.4–2.5)
0.922
Baseline CD4
<200 cells/µl
208 (31.8)
50 (58.1)
≥200 cells/µl
446 (68.2)
36 (41.9)
3.3 (1.8–4.7)
<0.001
3.4 (2.0–5.7)
<0.001
Anemia state
Mild anemia
138 (21.1)
09 (10.5)
0.4 (0.2–0.9)
0.023
Mo anemia
078 (11.9)
10 (11.6)
1.0 (0.4–2.0)
0.936
Sev anemia
030 (04.6)
23 (26.7)
7.6 (4.1–13.9)
<0.001
6.6 (3.4–12.9)
<0.001
ART regimen
EFV based
532 (81.4)
65 (75.6)
0.3 (0.1–0.5)
<0.001
LPV based
002 (00.3)
02 (02.3)
2.6 (0.3–24.0)
0.810
NVP based
120 (18.3)
19 (22.1)
1.4 (0.8–2.3)
0.260
ART: antiretroviral therapy; CI: confidence interval; EFV: Efavirenz; LPV: Lopinavir; Mo anemia: moderate anemia; NVP: Nevirapine; OR: odds ratio; Sev anemia: severe anemia; TB: tuberculosis; WHO: World Health Organization.
