The Severity of Autism Is Associated with Toxic Metal Body Burden and Red Blood Cell Glutathione Levels

Table 4

Correlation analyses of initial autism severity versus urinary metal excretion and initial glutathione. The metal excretion is measured both at Baseline (before DMSA) and after the 9th dose of DMSA. The first number in each cell is the correlation coefficient (r) and the second number is the P-value. Correlation coefficients with P < .05 are in bold. The last 2 rows list the total number of positive and negative correlation coefficients, respectively.

	ATEC total	ADOS (social + communication)	SAS	PDD-BI (modified autism score)
PbBase	−0.00 (0.96)	0.11 (0.47)	0.50 (0.0002)	0.22 (0.12)
SnBase	0.16 (0.32)	−0.11 (0.47)	0.12 (0.41)	0.09 (0.52)
TlBase	0.13 (0.32)	0.10 (0.49)	0.21 (0.15)	0.25 (0.077)
HgBase	0.13 (0.33)	0.05 (0.76)	0.15 (0.31)	0.18 (0.19)
SbBase	0.40 (0.002)	0.35 (0.02)	0.51 (0.0002)	0.42 (0.0023)
Wbase	0.16 (0.23)	0.07 (0.67)	0.26 (0.07)	0.17 (0.22)
AsBase	0.04 (0.74)	−0.05 (0.73)	0.00 (0.98)	0.04 (0.76)
CdBase	0.00 (1.00)	0.11 (0.48)	0.03 (0.83)	−0.10 (0.48)
AlBase	−0.06 (0.65)	−0.19 (0.20)	−0.05 (0.73)	0.02 (0.87)
Pb9	0.27 (0.04)	0.34 (0.02)	0.36 (0.01)	0.42 (0.0027)
Sn9	−0.02 (0.88)	0.00 (0.98)	0.02 (0.87)	−0.12 (0.42)
Tl9	0.26 (0.046)	0.11 (0.51)	0.27 (0.064)	0.24 (0.098)
Hg9	0.09 (0.52)	0.20 (0.18)	−0.02 (0.91)	0.07 (0.59)
Sb9	0.03 (0.84)	0.20 (0.19)	0.38 (0.008)	0.26 (0.065)
W9	0.11 (0.42)	0.34 (0.02)	−0.00 (0.99)	0.19 (0.18)
As9	0.19 (0.16)	−0.24 (0.12)	−0.24 (0.11)	−0.04 (0.79)
Cd9	0.07 (0.58)	0.34 (0.024)	0.08 (0.57)	0.15 (0.29)
Al9	0.06 (0.65)	0.28 (0.059)	0.25 (0.089)	0.17 (0.24)
Glut1	0.25 (0.04)	0.34 (0.024)	0.25 (0.09)	0.26 (0.70)
Number of positive coefficients	17	15	15	16
Number of negative coefficients	2	4	4	3