Table 5: Regression analyses of initial autism severity versus urinary metal excretion and initial glutathione. In the regression equation, the suffixes for the metals refer to the value at Baseline (B) and after the 9th ( 9) dose of DMSA in Phase 1.

Adjusted -valueEquationMost significant variables

ATEC0.22.00324.1–6.17 HgB + 76.6 SbB + 0.593 Pb9 + 3.97 Hg9 + 0.27 As9SbB , Pb9
SAS0.36.0024.81 + 1.70 PbB + 4.87 TlB − 0.640 HgB + 5.48 SbB − 1.87 CdB − 0.0237 AlB − 0.114 Pb9 − 3.14 Tl9 + 6.07 Sb9PbB
ADOS (comm. + social)0.45.000313.19–4.29 HgB + 24.1 SbB − 3.67 WB − 0.0673 AlB + 2.75 Hg9 + 6.60 W9 − 0.0539 As9 + 0.0054 GlutHgB , SbB , Hg9 , W9
PDD-BI (modified autism score)0.25.004−131.8 + 70.4 WB − 0.789 Sn9 + 18.8 Hg9 + 255 Sb9 + 21.8 W9Sb9 , WB , Sn9

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