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Table 6: Regression analyses of initial ados subscales versus urinary metal excretion and initial glutathione. In the regression equation, the suffixes for the metals refer to the value at Baseline (B) and after the 9th ( 9) dose of DMSA in Phase 1.

Adjusted -value Equation Most significant variables ADOS-Sociability 0.41 0.004 8.70 +1.20 PbB + 0.217 SnB + 12.7 TlB − 1.64 HgB − 10.2 SbB − 2.61 CdB − 0.631 AlB − 0.186 Pb9 − 7.13 Tl9 + 6.27 Sb9 +6.15 W9 +3.62 Cd9 W9, AlB, TlB, HgB, Pb9, Tl9 ADOS-Commun. 0.37 0.0003 2.39–2.57 HgB + 23.1 SbB + 2.32 Hg9 + .0048 Glut HgB, Hg9, SbB ADOS-Play 0.24 0.004 1.20 + 0.540 PbB + 4.23 Sb9 + 0.0017 Glut PbB ADOS-SBRI 0.21 0.02 4.64–0.897 HgB − 2.63 CdB − 0.26 AlB + 0.050 Pb9 + 0.730 Hg9

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