- About this Journal ·
- Abstracting and Indexing ·
- Advance Access ·
- Aims and Scope ·
- Article Processing Charges ·
- Articles in Press ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
Journal of Toxicology
Volume 2011 (2011), Article ID 910180, 7 pages
Ethylene Oxide: Acute Four-Hour and One-Hour Inhalation Toxicity Testing in Rats
1Snellings Toxicology Consulting, LLC, 23 Trails End Lane, Ridgefield, CT 06877, USA
2Inhalation Department, Bushy Run Research Center, R.D. 4, Mellon Road, Export, PA 15632, USA
3Toxicology and Environmental Research and Consulting, The Dow Chemical Company, 1803 Building, Midland, MI 48674, USA
Received 3 March 2011; Revised 30 April 2011; Accepted 19 May 2011
Academic Editor: Cinta Porte
Copyright © 2011 William M. Snellings et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- US Department of Transportation, Emergency Response Guidebook, ERG 2008, PHMSA, Washington, DC, USA, 2008.
- C. P. Waite, F. A. Patty, and W. P. Yang, “Acute response of guinea pigs to vapors of some new commercial organic compounds. IV. Ethylene oxide,” Public Health Reports, vol. 45, pp. 1832–1843, 1930.
- W. J. G. Walker and C. E. Greeson, “The toxicity of ethylene oxide,” The Journal of Hygiene, vol. 32, no. 3, pp. 409–416, 1932.
- ACGIH, “Documentation of the threshold limit values, committee on threshold limit values,” in Proceedings of the 24th Annual Meeting of the American Conference of Governmental Industrial Hygienists, (ACGIH '62), pp. 49–50, May 1962.
- K. H. Jacobson, E. B. Hackley, and L. Feinsliver, “The toxicity of inhaled ethylene oxide and propylene oxide vapors,” Archives of Industrial Health, vol. 13, no. 3, pp. 237–244, 1956.
- C. P. Carpenter, H. F. Smyth, and U. C. Pozzani, “The assay of acute vapor toxicity, and the grading and interpretation of results on 96 chemical compounds,” The Journal of Industrial Hygiene and Toxicology, vol. 31, no. 6, pp. 343–349, 1949.
- R. J. Sexton and E. V. Henson, “Dermatological injuries by ethylene oxide,” The Journal of Industrial Hygiene and Toxicology, vol. 31, no. 5, pp. 297–300, 1949.
- RTECS, The Registry of Toxic Effects of Chemical Substances, Number: KX2450000, National Institute for Occupational Safety and Health, Atlanta, Ga, USA, 2009.
- W. B. Deichmann and H. W. Gerarde, Toxicology of Drugs and Chemicals, Academic Press, New York, NY, USA, 1969.
- DOT, “49 CFR Ch. I (10—1—98 Edition), Part 173—Shippers-General requirements for shipments and packaging, § 173.132 Class 6, Division 6.1,” 1998.
- National Research Council, Acute Exposure Guideline Levels for Selected Airborne Chemicals, Volume 9, The National Academies Press, Washington, DC, USA, 2010.
- W. R. Thompson, “Use of moving averages and interpolation to estimate medium-effective dose,” Bacteriological Reviews, vol. 11, no. 2, pp. 115–145, 1947.
- A. M. Thiess, “Observations concerning intoxication due to ethylene oxide exposure,” Archives of Toxicology, vol. 20, p. 127, 1963.
- W. F. ten Berge, A. Zwart, and L. M. Appelman, “Concentration-time mortality response relationship of irritant and systemically acting vapours and gases,” Journal of Hazardous Materials, vol. 13, no. 3, pp. 301–309, 1986.