Potassium Channels Blockers from the Venom of Androctonus mauretanicus mauretanicus
Figure 3
Amino acid sequence and 3D structure of KTX. The crucial amino acid residues involved in the receptor recognition are in red and are materialized on the 3D structure according to Lange et al., 2006 [13]. The α-helix is in green, the β-sheet in red. Arrows in red indicate the three peptides able to compete (Kd = 100 nM) with the 125I-KTX bound to its binding site on rat brain synaptosomes [41].
